Description

At Viridian, we are focused on developing best-in-class medicines for people living with autoimmune and rare diseases. Leveraging our team’s expertise in antibody discovery and engineering, we have created a robust pipeline of differentiated investigational therapeutic candidates for well-validated targets.

Reporting to the Associate Director, Antibody Discovery and Engineering, the Scientist, Antibody Discovery and Engineering will be responsible for development and execution of therapeutic antibody discovery and optimization campaigns, working with research team to screen discovery molecules, and generate critical data to enable clinical candidate selection.  

This role may be based in our Waltham, MA headquarters, which would be a hybrid role, or it can also be fully remote. Our office-based employees are required to work in the office three (3) days a week. If remote, travel to headquarters for meetings would be required at the discretion of management. 

Responsibilities (including, but not limited to):

• Lead/participate in the generation, design, characterization, and developability assessment of therapeutic antibodies and other biotherapeutic formats
• Contribute to design and execution of screening cascade to generate and optimize lead antibodies with desired pharmacological and biophysical properties
• Contribute to data analysis, visualization, and interpretation of experimental findings
• Effectively communicate complex data and research progress with scientists, project teams and management
• Collaborate with and manage multiple external CRO partnerships to advance discovery initiatives, ensuring high-quality deliverables are met on time to support organizational objectives and timelines
• Review scientific literature on antibody technologies and therapeutic biology to propose innovative solutions to complex biological questions

Requirements

• Requires a Bachelor’s Degree and at least 7 years of experience or Master’s Degree and at least 5 years of experience, or PhD and at least 2 years of experience preferably in therapeutic antibody/protein development
• Solid background in protein sciences to support lead discovery and characterization, including protein sequence design, expression and purification strategies, protein characterization, binding and interaction analysis (BLI, SPR, flow cytometry, etc.)
• Demonstrated experience working with different antibody formats e.g. mAbs, Fabs, scFv, Vhh, Bispecific, multi specific, Fc fusions, and more                                            
• Demonstrated experience in lead antibody generation using hybridoma, single cell screening, and display technologies
• Demonstrated experience in antibody engineering, production, and characterization 
• Experience selecting and managing CRO’s for external research projects
• Strong written and verbal communication skills with the ability to effectively communicate scientific results
• Proven mindset of proactive continuous improvement
• Efficient independent worker with ability to focus and drive for results
• Strong attention to detail
• Ability to work in a fast-paced environment and to handle multiple tasks
• Strong commitment to ethical standards
• Proficient with Microsoft Office suite (i.e., Word, PowerPoint, Excel, Outlook, SharePoint, etc.)
• The salary range for this position is commensurate with experience
   

Viridian offers a comprehensive benefits package including:

• Competitive pay and stock options for all employees
• Competitive medical, dental, and vision plans
• Fertility and mental health programs
• Short- and long-term disability coverage
• Life, Travel and AD&D
• 401(k) Company Match with immediate company vest
• Employee Stock Purchase plan
• Generous vacation plan and paid company holiday shutdowns
• Various mental, financial, and proactive physical health programs covered by Viridian
   

Viridian Therapeutics, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination, harassment, or retaliation of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by Federal, State, and Local laws. Viridian will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Viridian Therapeutics, Inc participates in E-Verify, the federal program for electronic verification of employment eligibility.