Company Profile

Job DescriptionThe Formulation Research Scientist will work with other scientists dedicated to advancing drug candidates from exploratory development through commercial line extension in a Quality by Design (QbD) environment using lab based and computational tools to design and select dosage forms and manufacturing process. Key Duties and Responsibilities:Develop dosage forms for clinical and commercial use Develop stable and bioavailable formulations for different stages of development (e.g., ...

Job DescriptionGeneral Summary:The Biomarkers Senior Principal Research Scientist (Associate Director) is an independent leader with advanced scientific knowledge and expertise in biomarker development who develops and implements the clinical biomarker strategy for one or more programs and implements the biomarker plan during clinical development with no/minimal guidance. Experience in authoring and supporting regulatory filings and applicable areas of these filings is required. The incumbent ...

Job DescriptionVertex Pharmaceuticals Inc. is seeking a highly motivated and experienced Senior Scientist to join our Molecular and Cell Biology Department in San Diego. The successful candidate will play a crucial role in advancing our understanding of human genetic diseases and applying this knowledge to support innovative drug discovery and disease modeling efforts. The successful candidate will utilize advanced molecular biology technologies, genomics and bioinformatics approaches to inform ...

Job DescriptionGeneral Summary:The successful candidate will possess a deep knowledge of process chemistry skills for the development of synthetic routes, with knowledge and experience in early and mid to late-phase development and delivering drug substance under tight timelines. They will have a strong interest in laboratory work and will be key to driving the development of safe and scalable chemistry. They will spearhead the advancement of Vertex's early phase portfolio through personal ...

Job DescriptionWe are seeking a highly motivated computational biologist with a strong background in computational methods development to join Vertex. This position is part of a rapidly growing Data and Computational Sciences team focused on developing therapies for diseases with serious unmet need. You will play a critical key role in developing cutting-edge computational methods that assess the safety and efficacy of transformative therapeutics. You will also cross-functionally collaborate ...

Job DescriptionVertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases - cystic fibrosis, pain, sickle cell disease and transfusion-dependent beta thalassemia - and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of ...

Job DescriptionResearch Scientist, Computational Drug DesignGeneral Summary:We are seeking a highly motivated and experienced computational chemist to join our Computational Drug Design group in Boston. This individual will be responsible for contributing to both hit/lead identification and optimization programs using methods encompassing all computational aspects of drug discovery. The right candidate's responsibilities include close interaction with interdisciplinary projects teams to identify ...

Job DescriptionGeneral Summary:Vertex is seeking a talented individual to join our process chemistry group in Boston, MA. This role will support drug substance development programs at Vertex performing synthetic organic chemistry in the laboratory at a high level to design and execute syntheses of challenging compounds, troubleshoot a diverse range of chemistry issues and devise corrective solutions, and analyze complex data sets that leads to clear conclusion or recommendations to guide the ...

Job DescriptionThe Senior Principal Research Scientist is self-reliant with a proven record of accomplishments, both leading others in a matrix environment, and independently identifying and solving complex problems using sophisticated scientific methods and analytical thought, across a number of critical and diverse projects. This position reports to the Distinguished Fellow in charge of the Cell and Gene Therapy Research Discovery Team. The Senior Principal Research Scientist encourages ...

Job DescriptionGeneral Summary:The Principal Research Scientist, Lipid Chemist for Non-Viral Delivery, is self-reliant with a strong record of accomplishments, independently identifying and solving tough problems, repeatedly, across a number of critical and diverse projects. The Principal Research Scientist innovates proficiently and generates insights that influence research strategies. Responsibilities will include the design and synthesis of lipids within a project. Demonstrates resourcefulness ...