Company Profile

Vertex Pharmaceuticals

Company Overview

At Vertex, we bring together the brightest minds in the relentless pursuit of creating transformative medicines for people with serious and life-threatening diseases. Founded in 1989 in Cambridge, Massachusetts, we are one of only a handful of biotechnology companies founded since 1976 that has discovered and developed four or more approved medicines in our own labs. In addition to the four medicines we’ve developed to treat the underlying cause of cystic fibrosis, we have ongoing research programs focused on the underlying mechanisms of other serious diseases.

Our U.S. headquarters are in Boston’s Innovation District, our International headquarters are located in London, UK, and we have research and development (R&D) sites and commercial offices in the U.S., Europe, Canada, Australia and Latin America. With more than two-thirds of our employees dedicated to research and development (R&D), we are consistently recognized as one of the industry’s top places to work, including nine consecutive years on Science magazine’s Top Employers list. For company updates and to learn more about us visit www.vrtx.com. You can also get to know us on Facebook, Twitter and YouTube.

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  • < a day ago

    Medicinal Chemistry Scale-up Research Scientist

    Vertex Pharmaceuticals - Oxford, United Kingdom
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    Job DescriptionPOSITION SUMMARY:The Research Scientist will play a key role in the Medicinal Chemistry Scale-Up Group, working with a high degree of independence to synthesize small molecule drug candidates and intermediates on scales ranging from multi-grams to hundreds of grams for evaluation. The role requires advanced experimental troubleshooting, process optimization, and the ability to execute complex experimental procedures. The successful candidate will demonstrate resourcefulness, ...

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  • 4 days ago

    Analytical Development Scientist

    Vertex Pharmaceuticals - Boston, Massachusetts, United States
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    Job DescriptionEmployer: Vertex Pharmaceuticals Incorporated JOBTITLE: Analytical Development Scientist LOCATION: 316 - 318 Northern Avenue, Boston, Massachusetts 02210 OPENINGS:1 DUTIES: Perform a variety of well-defined, supportive functions including leading design and execution of analytical procedures that support development of cell therapy products. Develop, qualify and validate new test methods for characterization, purity and potency of hESCs and iPSC derived cell intermediates ...

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  • 7 days ago

    In Vitro ADME Principal Scientist

    Vertex Pharmaceuticals - Oxford, United Kingdom
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    Job DescriptionJob Summary:We are seeking a highly skilled and motivated In Vitro ADME Principal Scientist to join our dynamic team. The successful candidate will play a key role in supporting drug discovery and development programs by providing expert scientific and practical input into in vitro ADME (Absorption, Distribution, Metabolism, and Excretion) assays. This position requires a strong background in ADME & DMPK science, hands-on experience of assay development, and the ability to supervise ...

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  • 8 days ago

    Senior Research Scientist, Human Cell Engineering and In Vitro Disease Modeling

    Vertex Pharmaceuticals - San Diego, California, United States
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    Job DescriptionVertex Pharmaceuticals is seeking a highly skilled and motivated Senior Research Scientist to join our Disease Modeling Group. In this role, you will be responsible for the development of engineered human cell models and their integration into drug discovery workflows, supporting translational relevance and enabling the advancement of Vertex's pipeline. You will apply expertise in human cell biology, primary cell systems, iPSC technologies, and gene editing to develop robust ...

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  • 16 days ago

    Senior Principal Scientist Biotransformation

    Vertex Pharmaceuticals - Oxford, United Kingdom
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    Job DescriptionGeneral Summary:Vertex is seeking a highly motivated and experienced Senior Principal Biotransformation Scientist to join our Oxford team. The successful candidate will play a leading role in the delivery of biotransformation and metabolite characterization support to our drug discovery and development projects. The successful candidate will have a deep analytical background in high resolution mass spectrometry and metabolite identification with an established track record for ...

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  • 18 days ago

    Computational Genomics Research Scientist

    Vertex Pharmaceuticals - San Diego, California, United States
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    Job DescriptionWe are seeking a computational biologist with a strong track record of advancing biological discoveries through data analyses to join the Vertex Data and Computational Sciences (DCS) organization. In this role, you will leverage cutting-edge computational biology to accelerate the development of transformative therapies for serious human diseases. As a member of cross-functional disease project teams, you will contribute to the development of novel therapies in areas including ...

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